Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | TP53 | P04637 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819998 | 0.86 | GAA (0.44) | GAARAB9ANPC1POLBCASP3 | |
| SCHEMBL9295952 | 0.83 | GAA (0.47) | GAARAB9ANPC1POLBCASP3 | |
| SCHEMBL9819961 | 0.83 | GAA (0.43) | GAARAB9ANPC1POLBCASP3 | |
| SCHEMBL9820046 | 0.83 | GRIN1 (0.36) | RAB9ANPC1POLBMAPTSMN1; SMN2 | |
| SCHEMBL9819945 | 0.80 | MEN1 (0.41) | GAARAB9ANPC1POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL10352405 | 0.79 | PKM (0.36) | GAARAB9ANPC1POLBCASP3 | |
| SCHEMBL9820082 | 0.71 | MCL1 (0.35) | POLBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9836825 | 0.71 | AKR1B1 (0.39) | POLBMAPTALDH1A1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL9295550 | 0.70 | PKM (0.37) | GAARAB9ANPC1POLBCASP3 | |
| SCHEMBL10351910 | 0.69 | RAB9A (0.34) | GAARAB9ANPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210559-B1 | N-ACYLDIHYDRORESORUFIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE FOR THE DETERMINATION OF HYDROGEN PEROXIDE, PEROXIDATICALLY ACTIVE COMPOUNDS, OR PEROXIDASE | Roche Diagnostics GmbH (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0209875-B1 | RESORUFIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0210559-A2 | N-Acyldihydroresorufin derivatives, process for their preparation as well as their use for the determination of hydrogen peroxide, peroxidatically active compounds, or peroxidase | Roche Diagnostics GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209875-A1 | Resorufin derivatives and process for their preparation | Roche Diagnostics GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |