SCHEMBL27320487

SCHEMBL27320487

CC(CCN1CCN(C(=O)O)CC1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819950 0.85 ALDH1A1 (0.62) KDM4EALDH1A1POLB
SCHEMBL8777949 0.79 ALDH1A1 (0.54) KDM4EALDH1A1
SCHEMBL27589258 0.78 KDM4E (0.48) KDM4EALDH1A1
SCHEMBL9373661 0.78 KDM4E (0.71) KDM4EALDH1A1
SCHEMBL4315666 0.77 PIK3CD (0.46) KDM4EALDH1A1POLB
SCHEMBL22320488 0.77 PIK3CD (0.41) KDM4EALDH1A1POLB
SCHEMBL10649778 0.76 SIGMAR1 (0.56)
SCHEMBL15220059 0.76 ACHE (0.54) ALDH1A1
SCHEMBL10413779 0.76 FAAH (0.66) KDM4ESLC6A3
SCHEMBL7500758 0.75 CARM1 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 CN disclosed