⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393524 | 0.76 | — | — | |
| SCHEMBL396933 | 0.73 | — | — | |
| SCHEMBL9841926 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL35611 | 0.70 | — | — | |
| SCHEMBL9715048 | 0.68 | — | — | |
| SCHEMBL9715054 | 0.67 | — | — | |
| SCHEMBL6907077 | 0.65 | — | — | |
| SCHEMBL393525 | 0.62 | TSHR (0.40) | — | |
| SCHEMBL396291 | 0.62 | — | — | |
| SCHEMBL10246580 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | disclosed |
| EP-0215817-A1 | CONTINUOUS-WEAR LENSES. | BAUSCH & LOMB (US) | 1987-04-01 | — | — | EP | disclosed |
| WO-1986004341-A1 | CONTINUOUS-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |
| US-4535138-A | Silane ester contact lens composition, article and method of manufacture | PARAGON OPTICAL, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4419505-A | HYDROXYSILYLALKYL (METH)ACRYLATE COPOLYMER | PARAGON OPTICAL, INC. (US) | 1983-12-06 | — | — | US | disclosed |