Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390674 | 0.91 | ALDH1A1 (0.62) | PRSS1KAT2BALDH1A1TSHRTDP1 | |
| SCHEMBL109433 | 0.91 | ALDH1A1 (0.62) | PRSS1KAT2BALDH1A1TSHRTDP1 | |
| SCHEMBL14155094 | 0.84 | GSTM2 (0.54) | PRSS1KAT2BALDH1A1TSHRTDP1 | |
| SCHEMBL19972855 | 0.84 | HCAR3 (0.66) | PRSS1KAT2BALDH1A1MAPTHCAR3 | |
| SCHEMBL6233037 | 0.84 | ALDH1A1 (0.67) | PRSS1KAT2BALDH1A1TSHRTDP1 | |
| SCHEMBL111519 | 0.84 | PRSS1 (0.55) | PRSS1KAT2BALDH1A1TSHRTDP1 | |
| SCHEMBL8645160 | 0.84 | ALDH1A1 (0.57) | PRSS1KAT2BALDH1A1TSHRTDP1 | |
| SCHEMBL8804352 | 0.83 | PRSS1 (0.54) | PRSS1KAT2BMAPTHCAR3POLB | |
| SCHEMBL21141858 | 0.83 | MAPK1 (0.46) | PRSS1KAT2BALDH1A1TSHRTDP1 | |
| SCHEMBL2469009 | 0.83 | KAT2B (0.58) | PRSS1KAT2BALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226973-B1 | 4-BIS(2'-HYDROXYETHYL)AMINO-1-(3'-HYDROXYPROPYL)AMINO-2-NITRO-BENZENE, PROCESS FOR ITS PREPARATION AND MEANS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | claimed |
| EP-0226973-B1 | 4-BIS(2'-HYDROXYETHYL)AMINO-1-(3'-HYDROXYPROPYL)AMINO-2-NITRO-BENZENE, PROCESS FOR ITS PREPARATION AND MEANS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0226973-A2 | 4-Bis(2'-hydroxyethyl)amino-1-(3'-hydroxypropyl)amino-2-nitro-benzene, process for its preparation and means for dyeing hair | Wella Aktiengesellschaft (DE) | 1987-07-01 | — | — | EP | disclosed |