Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.66 |
| ▸ | GSK3B | P49841 | 3/20 | 0.66 |
| ▸ | PLK4 | O00444 | 2/20 | 0.66 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.66 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.66 |
| ▸ | RET | P07949 | 2/20 | 0.66 |
| ▸ | FER | P16591 | 2/20 | 0.66 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.66 |
| ▸ | CDK2 | P24941 | 2/20 | 0.66 |
| ▸ | MARK3 | P27448 | 2/20 | 0.66 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.66 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.66 |
| ▸ | STK3 | Q13188 | 2/20 | 0.66 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.66 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.66 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.66 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820168 | 0.85 | DYRK1A (0.57) | RPS6KA3GSK3BPLK4DAPK3DYRK3 | |
| SCHEMBL5256323 | 0.83 | PLK4 (0.57) | RPS6KA3GSK3BPLK4DAPK3DYRK3 | |
| SCHEMBL5259065 | 0.83 | MAPK14 (0.61) | RPS6KA3GSK3BPLK4DAPK3DYRK3 | |
| SCHEMBL27565066 | 0.76 | MAPK14 (0.62) | RPS6KA3GSK3BPLK4DAPK3DYRK3 | |
| SCHEMBL8112141 | 0.76 | CLK4 (0.46) | RPS6KA3GSK3BPLK4DAPK3DYRK3 | |
| SCHEMBL6333104 | 0.76 | MAPK14 (0.47) | RPS6KA3GSK3BPLK4DAPK3DYRK3 | |
| SCHEMBL6235341 | 0.71 | EGFR (0.77) | GSK3BCDK1MAPK1EGFRPDGFRB | |
| SCHEMBL5231898 | 0.71 | KDM4E (0.62) | RPS6KA3KDRMAPK1NPSR1MAPT | |
| SCHEMBL5865715 | 0.69 | AKT2 (0.68) | RPS6KA3MAPK1NPSR1GAAHPGD | |
| SCHEMBL5820038 | 0.69 | MAPK1 (1.00) | RPS6KA3MAP4K4LIMK1AURKBCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248523-B1 | PYRAZOLES | FISONS plc (GB) | 1991-10-16 | — | — | EP | disclosed |