Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 11/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 11/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458121 | 0.81 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL11759345 | 0.81 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Tolonidine SCHEMBL310600 | 0.78 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Tolonidine SCHEMBL29391908 | 0.78 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL11859273 | 0.74 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL6935250 | 0.73 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CLMNANISCH | |
| Hydrochloric Acid SCHEMBL7866932 | 0.72 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CLMNANISCH | |
| SCHEMBL11359884 | 0.72 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Tolonidine SCHEMBL871225 | 0.70 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL31442157 | 0.70 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170193-B1 | FEEDSTUFF ADDITIVE FOR THE GROWTH PROMOTING OF AGRICULTURAL USEFUL ANIMALS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1991-12-27 | — | — | EP | claimed |
| US-4853402-A | 2-SUBSTITUTED-2-IMIDAZOLINES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1989-08-01 | — | — | US | claimed |
| EP-0170193-B1 | FEEDSTUFF ADDITIVE FOR THE GROWTH PROMOTING OF AGRICULTURAL USEFUL ANIMALS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1991-12-27 | — | — | EP | disclosed |
| US-4970208-A | OXAZOLO-OR THIAZOLO 5,4-d!AZEPINES | BOEHRINGER INGELHEIM GMBH (DE) | 1990-11-13 | — | — | US | disclosed |
| US-4853402-A | 2-SUBSTITUTED-2-IMIDAZOLINES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1989-08-01 | — | — | US | disclosed |
| EP-0170193-A2 | Feedstuff additive for the growth promoting of agricultural useful animals | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1986-02-05 | — | — | EP | disclosed |