Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820333 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1TDP1MAPTMEN1TTR | |
| SCHEMBL14892862 | 0.85 | MAPT (0.44) | ALDH1A1TDP1MAPTMEN1TTR | |
| SCHEMBL14892845 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL2718367 | 0.79 | MAPT (0.44) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL31276471 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTMEN1TTR | |
| SCHEMBL9820288 | 0.77 | TDP1 (0.53) | ALDH1A1TDP1MAPTMEN1TTR | |
| SCHEMBL31047331 | 0.77 | TDP1 (0.53) | ALDH1A1TDP1MAPTMEN1TTR | |
| SCHEMBL14893069 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL8537615 | 0.75 | TDP1 (0.44) | ALDH1A1TDP1MAPTMEN1TTR | |
| SCHEMBL7351987 | 0.74 | TDP1 (0.50) | ALDH1A1TDP1MAPTMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | claimed |