Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232035 | 0.91 | ALDH1A1 (0.43) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL14892862 | 0.88 | MAPT (0.44) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL14893069 | 0.80 | ALDH1A1 (0.41) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL6983628 | 0.80 | ALDH1A1 (0.43) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL17242666 | 0.79 | TSHR (0.45) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL25221130 | 0.79 | MAPT (0.36) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL9820274 | 0.79 | ALDH1A1 (0.42) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL17186886 | 0.79 | ALDH1A1 (0.42) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL5484250 | 0.79 | TSHR (0.44) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL2337048 | 0.78 | POLB (0.47) | MAPTALDH1A1LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |