Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820325 | 0.93 | LMNA (0.53) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9046650 | 0.85 | LMNA (0.60) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9043221 | 0.83 | DRD3 (0.60) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9148668 | 0.72 | LMNA (0.62) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9148662 | 0.72 | LMNA (0.62) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10474475 | 0.72 | KMT2A (0.70) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL13576345 | 0.72 | KMT2A (0.70) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9043957 | 0.72 | KMT2A (0.70) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9044640 | 0.71 | DPP4 (0.60) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10677290 | 0.71 | LMNA (0.71) | KDM4EALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057520-A | Water solubility | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |