Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716892 | 0.85 | RAB9A (0.61) | IDO1RAB9AAKR1C3ALDH1A1MAPT | |
| SCHEMBL4726351 | 0.85 | IDO1 (0.54) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL10465292 | 0.85 | MAOB (0.56) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL11099610 | 0.85 | IDO1 (0.58) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL3861179 | 0.84 | MEN1 (0.55) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL11255725 | 0.84 | HTT (0.56) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL10569487 | 0.84 | ACHE (0.58) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL11419632 | 0.83 | IDO1 (0.56) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL11685218 | 0.83 | RAB9A (0.49) | IDO1RAB9AAKR1C3MAOBHTT | |
| SCHEMBL5445040 | 0.83 | MAOB (0.54) | IDO1RAB9AAKR1C3MAOBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260042-B1 | 2-(1-OXO-1-IMINO-1-THIACYCLOALKYL)-THIOPENEM DERIVATIVES | PFIZER INC. (US) | 1991-12-27 | — | — | EP | disclosed |
| EP-0138539-B1 | 2-AZACYCLOALKYLTHIOPENEM DERIVATIVES | PFIZER INC. (US) | 1989-03-15 | — | — | EP | disclosed |
| EP-0138538-B1 | 2-DIOXACYCLOALKYLTHIOPENEM DERIVATIVES | PFIZER INC. (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4772597-A | ANTIBIOTICS | PFIZER INC. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0260042-A1 | 2-(1-Oxo-1-imino-1-thiacycloalkyl)-Thiopenem derivatives | PFIZER INC. (US) | 1988-03-16 | — | — | EP | disclosed |
| EP-0130025-B1 | 2-ALKYLTHIOPENEM DERIVATIVES | PFIZER INC. (US) | 1987-07-08 | — | — | EP | disclosed |
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4619924-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | disclosed |
| US-4614737-A | ANTIBIOTICS | PFIZER INC. (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0138539-A1 | 2-Azacycloalkylthiopenem derivatives | PFIZER INC. (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0130025-A1 | 2-Alkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-02 | — | — | EP | disclosed |