Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22697507 | 0.92 | ALDH1A1 (0.52) | ALDH1A1HPGDLMNACYP1A2TSHR | |
| SCHEMBL19604139 | 0.92 | ALDH1A1 (0.52) | ALDH1A1HPGDLMNACYP1A2TSHR | |
| SCHEMBL20536280 | 0.89 | MMP1 (0.48) | ALDH1A1HPGDLMNACYP1A2CA12 | |
| SCHEMBL3210666 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDLMNACYP1A2CA12 | |
| SCHEMBL19404635 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDLMNACA12CA2 | |
| SCHEMBL3310896 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDLMNACA12CA2 | |
| SCHEMBL26048394 | 0.86 | DNM1 (0.44) | ALDH1A1LMNACA12CA2TSHR | |
| SCHEMBL31050952 | 0.86 | DNM1 (0.44) | ALDH1A1LMNACA12CA2TSHR | |
| SCHEMBL16692096 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HPGDLMNATSHRHDAC3 | |
| SCHEMBL8382529 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HPGDLMNACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317588-B1 | ISOXAZOLES WITH NOOTROPIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1991-08-07 | — | — | EP | disclosed |
| EP-0317588-A1 | ISOXAZOLES WITH NOOTROPIC ACTIVITY. | ZAMBON SPA (IT) | 1989-05-31 | — | — | EP | disclosed |
| WO-1988009330-A1 | ISOXAZOLES WITH NOOTROPIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1988-12-01 | — | — | WO | disclosed |