Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568565 | 0.88 | KMT2A (0.44) | KMT2AOPRK1CYP1A2MAPTADORA1 | |
| SCHEMBL23170921 | 0.81 | KMT2A (0.70) | KMT2AOPRK1CYP1A2ADORA1ADORA2A | |
| SCHEMBL8273101 | 0.80 | ALDH1A1 (0.44) | KMT2AOPRK1MAPTADORA1ADORA2A | |
| SCHEMBL8287309 | 0.79 | ADORA1 (0.68) | KMT2AADORA1ADORA2A | |
| SCHEMBL8673009 | 0.78 | CCR1 (0.58) | KMT2AOPRK1CYP1A2MAPTGAA | |
| SCHEMBL13223118 | 0.77 | KMT2A (0.66) | KMT2AOPRK1CYP1A2MAPTADORA1 | |
| SCHEMBL3799140 | 0.77 | OPRK1 (0.50) | KMT2AOPRK1MAPTGAAKDM4E | |
| SCHEMBL13968415 | 0.76 | HTT (0.44) | MAPTKDM4EMETAP2 | |
| SCHEMBL17361074 | 0.76 | OPRK1 (0.48) | KMT2AOPRK1MAPTGAAKDM4E | |
| SCHEMBL2025555 | 0.75 | KMT2A (0.44) | KMT2AOPRK1MAPTADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673889-B2 | Substituted imidazo[4,5-c][1,8]naphthyridines as phosphodiesterase inhibitors | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| EP-0275520-B1 | SUBSTITUTED 1,8-NAPHTHYRIDINE DERIVATIVES AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1991-12-11 | — | — | EP | disclosed |
| US-4801592-A | FOR PLANTS, SEEDS, SOILS | BASF AKTIENGESELLSCHAFT (DE) | 1989-01-31 | — | — | US | disclosed |
| EP-0275520-A1 | Substituted 1,8-naphthyridine derivatives and fungicides containing them | BASF Aktiengesellschaft (DE) | 1988-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673889-B2 | Substituted imidazo[4,5-c][1,8]naphthyridines as phosphodiesterase inhibitors | ENPP1, ENPP3, PDE4A | KMT2A 3466/4885OPRK1 2687/4885CYP1A2 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.