Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268003 | 0.79 | SLC40A1 (0.43) | MAPTKDM4ELMNAHTR1AADRA1D | |
| SCHEMBL248690 | 0.75 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL13230455 | 0.75 | IDO1 (0.44) | MAPTKDM4ELMNAHTR1AADRA1D | |
| SCHEMBL15912059 | 0.75 | IDO1 (0.57) | MAPTTDP1KDM4ELMNAHTR1A | |
| SCHEMBL9820405 | 0.74 | ABCG2 (0.37) | MAPTALDH1A1ADORA3MAOAPTGS1 | |
| Hydrochloric Acid SCHEMBL696334 | 0.73 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| Hydrochloric Acid SCHEMBL695985 | 0.73 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL2478157 | 0.73 | MEN1 (0.57) | MAPTALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL30504562 | 0.73 | MEN1 (0.57) | MAPTALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL4251046 | 0.73 | MEN1 (0.60) | NPC1MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275520-B1 | SUBSTITUTED 1,8-NAPHTHYRIDINE DERIVATIVES AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1991-12-11 | — | — | EP | disclosed |