Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.63 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.63 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.61 |
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL695985 | 0.98 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| Hydrochloric Acid SCHEMBL696334 | 0.98 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL2478157 | 0.86 | MEN1 (0.57) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL30504562 | 0.86 | MEN1 (0.57) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| Hydrochloric Acid SCHEMBL28828326 | 0.84 | MEN1 (0.56) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| Hydrochloric Acid SCHEMBL6311928 | 0.84 | MEN1 (0.56) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL6752938 | 0.83 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL29005643 | 0.80 | NPC1 (0.49) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL4500702 | 0.79 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9902520 | 0.79 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103946-B1 | IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME | IMMUNDIAGNOSTIK AG (DE) | 2024-03-13 | — | — | EP | claimed |
| US-20230109016-A1 | IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME | IMMUNDIAGNOSTIK AG (DE) | 2023-04-06 | — | — | US | claimed |
| EP-4103946-A1 | IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME | Immundiagnostik AG (DE) | 2022-12-21 | — | — | EP | claimed |
| WO-2021160696-A1 | IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME | IMMUNDIAGNOSTIK AG (DE) | 2021-08-19 | — | — | WO | claimed |
| US-3996231-A | ANTIINFLAMMATORY, ANALGESICS | CHOAY S.A. (FR) | 1976-12-07 | — | — | US | claimed |
| EP-4596537-A1 | NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF | JD Bioscience Inc. (KR) | 2025-08-06 | — | — | EP | disclosed |
| CN-119552120-A | Pyrazole and imidazole compounds for inhibiting IL-17 and rory | 里亚塔医药公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-112654610-B | Pyrazole and imidazole compounds for inhibiting IL-17 and rory | 里亚塔医药公司 | 2024-12-24 | — | — | CN | disclosed |
| US-20240398783-A1 | Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof | GISMO THERAPEUTICS, INC. | 2024-12-05 | — | — | US | disclosed |
| US-20240360084-A1 | PYRAZOLE AND IMIDAZOLE COMPOUNDS FOR INHIBITION OF IL-17 AND RORGAMMA | REATA PHARMACEUTICALS INC (US) | 2024-10-31 | — | — | US | disclosed |
| EP-3558969-B1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-18 | — | — | EP | disclosed |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-03 | — | — | US | disclosed |
| WO-1997010215-A1 | FUNGICIDAL QUINOLINES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-20 | — | — | WO | disclosed |
| EP-0304239-B1 | Reformed polysilazane and method of producing same | TOA NENRYO KOGYO KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-4975512-A | Crosslinking with amine, ammonium, hydrazine | PETROLEUM ENERGY CENTER (JP) | 1990-12-04 | — | — | US | disclosed |
| US-4880818-A | 1-Acyl-4-[1-(4-quinolinyl)-hydrazin-2-ylidene]piperidines and their use as hypotensive agents | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-11-14 | — | — | US | disclosed |
| US-4771052-A | Tetrahydropyrido[3',4':4,5]pyrrolo[2,3-c]quinolines and their use as hypotensive agents | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0277625-A2 | Tetrahydropyrido[3',4':4,5]pyrrolo[2,3-c]quinolines, intermediates and a process for the preparation thereof and their use as hypotensive agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-08-10 | — | — | EP | disclosed |
| US-3996231-A | ANTIINFLAMMATORY, ANALGESICS | CHOAY S.A. (FR) | 1976-12-07 | — | — | US | disclosed |
| US-3936444-A | FROM A LACTIM-ETHER AND AN ARYL OR HETEROARYL HYDRAZINE, ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240398783-A1 | Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof | PRNP, GBA1, GBA3 | HTR1A 1008/4885ADRA1D 3806/4885ADRA1A 3536/4885 |
| US-20240360084-A1 | PYRAZOLE AND IMIDAZOLE COMPOUNDS FOR INHIBITION OF IL-17 AND RORGAMMA | RORC, RORB, RORA | HTR1A 4525/4885ADRA1D 1471/4885ADRA1A 1173/4885 |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | MALT1, PPP3R1, SQSTM1 | HTR1A 2942/4885ADRA1D 2840/4885ADRA1A 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.