Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611748 | 0.89 | FAAH (0.47) | ALDH1A1KDM4EMIFKMT2AMAPT | |
| SCHEMBL9820633 | 0.89 | FAAH (0.47) | ALDH1A1KDM4EMIFKMT2AMAPT | |
| SCHEMBL9820637 | 0.89 | FAAH (0.47) | ALDH1A1KDM4EMIFKMT2AMAPT | |
| SCHEMBL9820503 | 0.80 | ABCG2 (0.42) | ALDH1A1KDM4EESR1KMT2AMEN1 | |
| SCHEMBL10613245 | 0.80 | ABCG2 (0.42) | ALDH1A1KDM4EESR1KMT2AMEN1 | |
| SCHEMBL9820519 | 0.79 | HPGD (0.46) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL9335450 | 0.76 | KDM4E (0.55) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL1486282 | 0.76 | FAAH (0.40) | NPSR1 | |
| SCHEMBL1486280 | 0.76 | FAAH (0.40) | NPSR1 | |
| SCHEMBL5606968 | 0.76 | KDM4E (0.55) | ALDH1A1KDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240184-B1 | ALPHA-METHYLCINNAMIC ACID ESTER DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4751018-A | DISCOLORATION INHIBITION | MITSUBISHI RAYON COMPANY LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0240184-A2 | Alpha-Methylcinnamic acid ester derivative and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |