Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611748 | 1.00 | FAAH (0.47) | FAAHALDH1A1CNR1CNR2KDM4E | |
| SCHEMBL9820633 | 1.00 | FAAH (0.47) | FAAHALDH1A1CNR1CNR2KDM4E | |
| SCHEMBL9820481 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2AMAPTABCG2 | |
| SCHEMBL10613245 | 0.89 | ABCG2 (0.42) | FAAHALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL9820503 | 0.89 | ABCG2 (0.42) | FAAHALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL10615169 | 0.83 | PLA2G4A (0.44) | ABCG2 | |
| SCHEMBL9820517 | 0.83 | PLA2G4A (0.44) | ABCG2 | |
| SCHEMBL10610895 | 0.81 | MAPT (0.42) | FAAHALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL9820459 | 0.81 | MAPT (0.42) | FAAHALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL10611552 | 0.81 | ALDH1A1 (0.48) | FAAHALDH1A1CNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240184-B1 | ALPHA-METHYLCINNAMIC ACID ESTER DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4751018-A | DISCOLORATION INHIBITION | MITSUBISHI RAYON COMPANY LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0240184-A2 | Alpha-Methylcinnamic acid ester derivative and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |