Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611552 | 0.92 | ALDH1A1 (0.48) | HPGDHSD17B10ALOX15KDM4EALDH1A1 | |
| SCHEMBL9820481 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL28429232 | 0.76 | ALDH1A1 (0.57) | HPGDHSD17B10ALOX15KDM4EALDH1A1 | |
| SCHEMBL9820503 | 0.75 | ABCG2 (0.42) | HPGDKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL10613245 | 0.75 | ABCG2 (0.42) | HPGDKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9820459 | 0.74 | MAPT (0.42) | HPGDKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL10610895 | 0.74 | MAPT (0.42) | HPGDKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL10611733 | 0.72 | NPC1 (0.52) | KMT2AMAPTLMNAPOLBCYP2D6 | |
| SCHEMBL10623765 | 0.72 | NPC1 (0.52) | KMT2AMAPTLMNAPOLBCYP2D6 | |
| SCHEMBL9820579 | 0.72 | NPC1 (0.52) | KMT2AMAPTLMNAPOLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240184-B1 | ALPHA-METHYLCINNAMIC ACID ESTER DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4751018-A | DISCOLORATION INHIBITION | MITSUBISHI RAYON COMPANY LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0240184-A2 | Alpha-Methylcinnamic acid ester derivative and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |