Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820532 | 0.78 | MGAM (0.50) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL9820493 | 0.72 | KDM4E (0.53) | RAB9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL29678599 | 0.71 | ALDH1A1 (0.65) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL8045944 | 0.71 | ALDH1A1 (0.65) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL3434993 | 0.71 | ALDH1A1 (1.00) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL9820531 | 0.70 | ALDH1A1 (0.46) | RAB9AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL28427835 | 0.68 | ALDH1A1 (0.45) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL10495113 | 0.68 | BCHE (0.35) | RAB9AALDH1A1GAAHPGDKMT2A | |
| SCHEMBL9532116 | 0.67 | KMT2A (0.50) | RAB9AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9820471 | 0.67 | TP53 (0.41) | RAB9AKDM4EKMT2ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217747-B1 | NEMATOCIDAL AGENTS | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | claimed |
| US-4694014-A | 1,3,4-THIADIAZOLES | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | claimed |
| EP-0217747-A2 | Nematocidal agents | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | claimed |
| EP-0217747-B1 | NEMATOCIDAL AGENTS | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| US-4694014-A | 1,3,4-THIADIAZOLES | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0217747-A2 | Nematocidal agents | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |