Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | SI | P14410 | 3/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820471 | 0.85 | TP53 (0.41) | KDM4EMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL9820562 | 0.81 | HDAC1 (0.40) | NOTUMKDM4EMEN1KMT2APOLB | |
| SCHEMBL9532116 | 0.81 | KMT2A (0.50) | GAAKDM4EMEN1KMT2APOLB | |
| SCHEMBL9820477 | 0.80 | MAPT (0.54) | KDM4EKMT2ALMNAPOLBRXFP1 | |
| SCHEMBL9820530 | 0.78 | RAB9A (0.55) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL10462996 | 0.75 | MGAM (0.49) | MGAMGAASIMGAM2NOTUM | |
| SCHEMBL10409512 | 0.73 | SMN1; SMN2 (0.54) | GAAKDM4EMEN1KMT2ALMNA | |
| SCHEMBL8707903 | 0.72 | KDM4E (0.67) | MGAMGAASIMGAM2NOTUM | |
| SCHEMBL9664681 | 0.71 | ALDH1A1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL9820493 | 0.70 | KDM4E (0.53) | NOTUMKDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217747-B1 | NEMATOCIDAL AGENTS | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | claimed |
| US-4694014-A | 1,3,4-THIADIAZOLES | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | claimed |
| EP-0217747-A2 | Nematocidal agents | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | claimed |
| EP-0217747-B1 | NEMATOCIDAL AGENTS | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| US-4694014-A | 1,3,4-THIADIAZOLES | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0217747-A2 | Nematocidal agents | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |