Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820687 | 0.85 | HSD17B10 (0.42) | MEN1KMT2ALMNANPSR1PDE4B | |
| SCHEMBL9820695 | 0.85 | CNR1 (0.43) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9820655 | 0.80 | BCL2L1 (0.44) | CNR1CNR2MEN1KMT2ATAS1R3 | |
| SCHEMBL4631386 | 0.78 | KDM4E (0.54) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9820804 | 0.77 | KDM4E (0.55) | ALDH1A1MEN1KMT2ALMNAPDE4B | |
| SCHEMBL30785090 | 0.77 | KDM4E (0.55) | ALDH1A1MEN1KMT2ALMNAPDE4B | |
| SCHEMBL27265229 | 0.76 | ALDH1A1 (0.40) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL26583286 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL4132557 | 0.74 | TAS1R3 (0.41) | CNR1CNR2ALDH1A1KMT2ATAS1R3 | |
| SCHEMBL8431119 | 0.73 | KDM4E (0.41) | PDE3BPDE3AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |