⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820623 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL9821074 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9820866 | 0.76 | — | — | |
| SCHEMBL9820812 | 0.72 | — | — | |
| SCHEMBL9821105 | 0.69 | — | — | |
| SCHEMBL9870554 | 0.68 | GAA (0.31) | — | |
| SCHEMBL9820587 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL9820808 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL9820671 | 0.66 | — | — | |
| SCHEMBL9820596 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |