Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870554 | 0.81 | GAA (0.31) | ALDH1A1 | |
| SCHEMBL9820890 | 0.81 | ALDH1A1 (0.31) | ALDH1A1HPGD | |
| SCHEMBL9820808 | 0.79 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL9820623 | 0.78 | — | — | |
| SCHEMBL9820794 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL9820668 | 0.69 | GAA (0.32) | ALDH1A1HPGD | |
| SCHEMBL9820937 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL9820866 | 0.66 | — | — | |
| SCHEMBL9820689 | 0.64 | — | — | |
| SCHEMBL9820865 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |