Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297794 | 1.00 | CYP19A1 (0.40) | CYP19A1SIGMAR1 | |
| SCHEMBL4767952 | 0.87 | GLB1 (0.37) | SIGMAR1 | |
| SCHEMBL15229389 | 0.77 | GBA1 (0.47) | — | |
| SCHEMBL7288409 | 0.76 | CYP19A1 (0.40) | CYP19A1SIGMAR1 | |
| SCHEMBL7297026 | 0.75 | MAOB (0.42) | CYP19A1SIGMAR1 | |
| SCHEMBL27644564 | 0.74 | GBA1 (0.41) | CYP19A1SIGMAR1 | |
| SCHEMBL9111411 | 0.73 | CYP19A1 (0.43) | CYP19A1SIGMAR1 | |
| SCHEMBL5563809 | 0.72 | LTA4H (0.50) | CYP19A1SIGMAR1 | |
| SCHEMBL5558725 | 0.72 | LTA4H (0.50) | CYP19A1SIGMAR1 | |
| SCHEMBL11537058 | 0.71 | GBA1 (0.58) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |