Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644564 | 0.98 | GBA1 (0.41) | CYP19A1GBA1SIGMAR1 | |
| SCHEMBL2089535 | 0.80 | ITGB3 (0.40) | SIGMAR1 | |
| SCHEMBL11537058 | 0.78 | GBA1 (0.58) | GBA1SIGMAR1 | |
| SCHEMBL27525435 | 0.77 | GBA1 (0.56) | GBA1SIGMAR1 | |
| SCHEMBL9820951 | 0.76 | CYP19A1 (0.40) | CYP19A1SIGMAR1 | |
| SCHEMBL7297794 | 0.76 | CYP19A1 (0.40) | CYP19A1SIGMAR1 | |
| SCHEMBL3358034 | 0.76 | GBA1 (0.59) | GBA1SIGMAR1 | |
| SCHEMBL29139845 | 0.72 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL82734 | 0.70 | GBA1 (0.61) | GBA1SIGMAR1 | |
| SCHEMBL9820891 | 0.70 | CYP19A1 (0.40) | CYP19A1GBA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |