Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820590 | 0.84 | MAPT (0.51) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL10532509 | 0.81 | CTSV (0.67) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL10721491 | 0.79 | AKR1C3 (0.53) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL10881308 | 0.77 | HTT (0.62) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL9821210 | 0.77 | MAPT (0.67) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL9821173 | 0.76 | MAPT (0.58) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL10532614 | 0.75 | LMNA (0.71) | MAPTMEN1KMT2AGAAATM | |
| SCHEMBL9820982 | 0.74 | MAPT (0.66) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL10718571 | 0.73 | CTSV (0.61) | MAPTMEN1KMT2AMAPK1GFER | |
| SCHEMBL9622919 | 0.72 | MAPT (0.46) | MAPTMEN1KMT2AMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282749-B1 | HAIR DYEING COMPOSITIONS CONTAINING DIRECT NITRODIPHENYLAMINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-08-28 | — | — | EP | disclosed |