Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12430465 | 0.82 | ACHE (0.44) | ACHEHDAC1HDAC6MAPTGSK3B | |
| SCHEMBL11743910 | 0.81 | GSK3B (0.47) | CA12CA1CA2CA4CA6 | |
| SCHEMBL246840 | 0.79 | ACHE (0.42) | ACHENPC1GSK3BPTPN1ALDH1A1 | |
| SCHEMBL11666165 | 0.79 | CA12 (0.38) | CA12CA1CA2CA4CA6 | |
| SCHEMBL1376911 | 0.78 | ALDH1A1 (0.52) | CA12CA1CA2CA4CA6 | |
| SCHEMBL3090722 | 0.76 | PARP1 (0.50) | CA12CA1CA2CA4CA6 | |
| SCHEMBL1008508 | 0.76 | CDC25B (0.55) | CA12CA1CA2CA4CA6 | |
| Hydrochloric Acid SCHEMBL11591120 | 0.76 | CHRM2 (0.40) | CA12CA1CA2CA4CA6 | |
| SCHEMBL4949504 | 0.76 | ACHE (0.42) | ACHEHDAC1HDAC6MAPTNPC1 | |
| SCHEMBL842236 | 0.75 | PRKCI (0.52) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163346-A | Synthesis method of o-bromo-p-fluoroacetanilide | 宁夏常晟药业有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114163346-A | Synthesis method of o-bromo-p-fluoroacetanilide | 宁夏常晟药业有限公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |