Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821165 | 0.77 | CYP11B1 (0.39) | TRPV4 | |
| SCHEMBL9821104 | 0.77 | ADRB2 (0.49) | — | |
| SCHEMBL9821113 | 0.76 | ADRB2 (0.41) | — | |
| SCHEMBL23564088 | 0.73 | TRPV4 (0.34) | TRPV4 | |
| SCHEMBL22763993 | 0.73 | SOS1 (0.36) | TRPV4 | |
| SCHEMBL9488312 | 0.71 | TRPV4 (0.41) | TRPV4 | |
| SCHEMBL23526350 | 0.70 | SOS1 (0.35) | TRPV4 | |
| SCHEMBL29945727 | 0.70 | SOS1 (0.35) | TRPV4 | |
| SCHEMBL23526352 | 0.70 | SOS1 (0.35) | TRPV4 | |
| SCHEMBL10717289 | 0.70 | SCN9A (0.31) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |