Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 7/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22763993 | 0.85 | SOS1 (0.36) | CYP11B1CYP11B2SOS1TRPV4 | |
| SCHEMBL29945727 | 0.81 | SOS1 (0.35) | CYP11B1CYP11B2SOS1TRPV4ADRB2 | |
| SCHEMBL23526352 | 0.81 | SOS1 (0.35) | CYP11B1CYP11B2SOS1TRPV4ADRB2 | |
| SCHEMBL23526350 | 0.81 | SOS1 (0.35) | CYP11B1CYP11B2SOS1TRPV4ADRB2 | |
| SCHEMBL9821104 | 0.78 | ADRB2 (0.49) | ADRB2ADRB1 | |
| SCHEMBL25688973 | 0.78 | CYP11B1 (0.46) | CYP11B1CYP11B2TRPV4 | |
| SCHEMBL9821039 | 0.77 | TRPV4 (0.30) | TRPV4 | |
| SCHEMBL23564088 | 0.77 | TRPV4 (0.34) | CYP11B1CYP11B2SOS1TRPV4 | |
| SCHEMBL23526362 | 0.76 | SOS1 (0.39) | SOS1 | |
| SCHEMBL23526365 | 0.76 | SOS1 (0.39) | SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |