Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195093 | 0.80 | PTPN1 (0.46) | GSK3BPTPN1CES2CES1POLB | |
| SCHEMBL16082919 | 0.80 | PTPN1 (0.46) | GSK3BPTPN1CES2CES1POLB | |
| SCHEMBL9821099 | 0.77 | SMN1; SMN2 (0.44) | CES2CES1POLBMEN1GAA | |
| SCHEMBL17767736 | 0.77 | CES2 (0.61) | GSK3BPTPN1CES2CES1 | |
| SCHEMBL14720123 | 0.75 | GSK3B (0.40) | GSK3BPTPN1POLBMEN1KMT2A | |
| SCHEMBL23317589 | 0.71 | GSK3B (0.44) | GSK3BPTPN1NOTUMGAAKMT2A | |
| SCHEMBL9488312 | 0.71 | TRPV4 (0.41) | CES2CES1NOTUMMEN1KMT2A | |
| SCHEMBL31277930 | 0.68 | ERN1 (0.46) | GSK3BPTPN1CES2CES1POLB | |
| SCHEMBL392810 | 0.68 | PTPN1 (0.50) | GSK3BPTPN1POLBMEN1GAA | |
| SCHEMBL14720176 | 0.68 | HPGDS (0.41) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |