SCHEMBL9821059

SCHEMBL9821059

CC(C)(C)NC(C)(O)c1cc(F)cc(C#N)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.36
ALB P02768 1/20 0.36
GRM5 P41594 1/20 0.33
IDH1 O75874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11966001 0.78 KIF11 (0.44) GRM5
SCHEMBL32670772 0.73 AKR1C3 (0.38)
SCHEMBL34468163 0.73 PLCG1 (0.40)
SCHEMBL25460768 0.73 PDK1 (0.35)
SCHEMBL25460810 0.73 GRM5 (0.31) GRM5
SCHEMBL22168989 0.72 GRM5 (0.35) GRM5
SCHEMBL29837993 0.72 KIF11 (0.45) GRM5
SCHEMBL628008 0.72 KIF11 (0.45) GRM5
SCHEMBL25968720 0.70 CNR1 (0.35) GRM5
SCHEMBL25167682 0.70 ALOX5 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0224001-B1 ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS AMERICAN CYANAMID COMPANY (US) 1991-03-20 EP disclosed
US-4863959-A Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals AMERICAN CYANAMID COMPANY (US) 1989-09-05 US disclosed
EP-0224001-A1 Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals AMERICAN CYANAMID COMPANY (US) 1987-06-03 EP disclosed