Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821054 | 0.84 | ADRB2 (0.36) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| SCHEMBL9821050 | 0.81 | LMNA (0.53) | ADRB2ADRB1TSHRHIF1AADRA1A | |
| SCHEMBL16412382 | 0.78 | SCN9A (0.43) | — | |
| SCHEMBL16412380 | 0.78 | SCN9A (0.43) | — | |
| SCHEMBL9706046 | 0.78 | TSHR (0.58) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| SCHEMBL26463822 | 0.77 | CYP11B1 (0.37) | — | |
| SCHEMBL10596908 | 0.76 | GRM5 (0.34) | MEN1KMT2A | |
| SCHEMBL12262985 | 0.73 | GRM5 (0.41) | — | |
| SCHEMBL10658170 | 0.73 | ADRB2 (0.64) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| SCHEMBL25632952 | 0.73 | SOS1 (0.39) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195396-B1 | 5-FLUOROBENZONITRILE DERIVATIVES AND PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF FOR INCREASING THE LEAN MEAT TO FAT RATIO, AND/OR ENHANCING THE GROWTH RATE OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1989-03-01 | — | — | EP | claimed |
| US-4614746-A | 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-30 | — | — | US | claimed |
| EP-0195396-A1 | 5-Fluorobenzonitrile derivatives and pharmacologically acceptable acid addition salts thereof for increasing the lean meat to fat ratio, and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | claimed |
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0195396-B1 | 5-FLUOROBENZONITRILE DERIVATIVES AND PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF FOR INCREASING THE LEAN MEAT TO FAT RATIO, AND/OR ENHANCING THE GROWTH RATE OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1989-03-01 | — | — | EP | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
| US-4614746-A | 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0195396-A1 | 5-Fluorobenzonitrile derivatives and pharmacologically acceptable acid addition salts thereof for increasing the lean meat to fat ratio, and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |