Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MTOR | P42345 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666064 | 0.84 | HIF1A (0.61) | TSHRADRB2ADRB1CYP1A2ADRB3 | |
| SCHEMBL6680502 | 0.82 | HIF1A (0.63) | TSHRADRB2ADRB1CYP1A2ADRB3 | |
| SCHEMBL14535391 | 0.81 | FAAH (0.45) | TSHRADRB2ADRB1ADRB3HIF1A | |
| SCHEMBL10606401 | 0.81 | ADRB2 (0.50) | TSHRADRB2ADRB1CYP1A2CYP3A4 | |
| SCHEMBL25933186 | 0.80 | GLA (0.42) | ADRA1AADRA1DADRA1B | |
| SCHEMBL9646909 | 0.79 | LMNA (0.52) | HIF1ALMNADRD2ADRA1D | |
| SCHEMBL27288216 | 0.78 | ADRB2 (0.51) | ADRB2ADRB3 | |
| SCHEMBL9821088 | 0.78 | ADRB2 (0.54) | TSHRADRB2ADRB1CYP1A2ADRB3 | |
| Metaterol SCHEMBL249460 | 0.78 | HIF1A (0.70) | TSHRADRB2ADRB1CYP1A2ADRB3 | |
| SCHEMBL4697927 | 0.77 | S1PR1 (0.45) | TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195397-A1 | m-Cyanophenethanolamines as animal growth promoters and antilipogenic agents | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | claimed |
| EP-0225165-B1 | USE OF PHENETHANOL AMINES TO IMPROVE FAT CONTENT OF SOWS' MILK | ELI LILLY AND COMPANY (US) | 1992-08-26 | — | — | EP | disclosed |
| US-4904662-A | Raising of pigs | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0195397-B1 | M-CYANOPHENETHANOLAMINES AS ANIMAL GROWTH PROMOTERS AND ANTILIPOGENIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-12-13 | — | — | EP | disclosed |
| EP-0225165-A2 | Use of phenethanol amines to improve fat content of sows' milk | ELI LILLY AND COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |
| EP-0195397-A1 | m-Cyanophenethanolamines as animal growth promoters and antilipogenic agents | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |