Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 2/20 | 0.30 |
| ▸ | ALPI | P09923 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822160 | 0.83 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2PDE4B | |
| SCHEMBL9822393 | 0.81 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2RECQL | |
| SCHEMBL9822209 | 0.80 | RECQL (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2RECQL | |
| SCHEMBL10396606 | 0.79 | RECQL (0.36) | KDM4EALDH1A1HPGDSMN1; SMN2RECQL | |
| SCHEMBL9822039 | 0.79 | RECQL (0.33) | ALDH1A1RECQLHTT | |
| SCHEMBL9822230 | 0.74 | HCAR2 (0.39) | KDM4EALDH1A1HPGDRECQLHTT | |
| SCHEMBL10414519 | 0.73 | SORD (0.38) | KDM4EALDH1A1HPGDSMN1; SMN2PDE4B | |
| SCHEMBL9822481 | 0.73 | KDM4E (0.35) | KDM4EALDH1A1HPGDL3MBTL1RECQL | |
| SCHEMBL9822158 | 0.72 | PKM (0.35) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL10407281 | 0.69 | KMT2A (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |