Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821971 | 0.97 | KDM1A (0.33) | PKMACHELMNAMEN1MAPK1 | |
| SCHEMBL9822221 | 0.88 | PKM (0.34) | PKMPOLBACHELMNAMEN1 | |
| SCHEMBL9822165 | 0.85 | KDM4E (0.32) | PKMPOLBLMNAALDH1A1MEN1 | |
| SCHEMBL9822171 | 0.83 | PKM (0.35) | PKMPOLBCHRNEACHELMNA | |
| SCHEMBL9822104 | 0.81 | PKM (0.36) | PKMPOLBLMNA | |
| SCHEMBL3582081 | 0.80 | PKM (0.48) | PKMPOLBLMNAALDH1A1MEN1 | |
| SCHEMBL9822417 | 0.80 | LMNA (0.35) | PKMPOLBACHELMNAALDH1A1 | |
| SCHEMBL9822255 | 0.78 | LMNA (0.33) | PKMLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10408138 | 0.77 | PKM (0.46) | PKMPOLBACHELMNAALDH1A1 | |
| SCHEMBL10407382 | 0.74 | POLB (0.40) | PKMPOLBACHEALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |