Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822165 | 0.97 | KDM4E (0.32) | PKMRECQLPOLBLMNAKDM4E | |
| SCHEMBL9822175 | 0.88 | PKM (0.36) | PKMRECQLPOLBCYP1A2LMNA | |
| SCHEMBL9821971 | 0.85 | KDM1A (0.33) | PKMLMNAKDM4EMEN1KMT2A | |
| SCHEMBL10397427 | 0.81 | LMNA (0.33) | PKMRECQLPOLBLMNAKDM4E | |
| SCHEMBL9822104 | 0.78 | PKM (0.36) | PKMPOLBGAALMNA | |
| SCHEMBL9822255 | 0.75 | LMNA (0.33) | PKMRECQLLMNAMEN1KMT2A | |
| SCHEMBL10408138 | 0.74 | PKM (0.46) | PKMRECQLPOLBGAACYP1A2 | |
| SCHEMBL10407382 | 0.72 | POLB (0.40) | PKMRECQLPOLBGAACYP1A2 | |
| SCHEMBL9822171 | 0.72 | PKM (0.35) | PKMRECQLPOLBCYP1A2LMNA | |
| SCHEMBL9822021 | 0.71 | PKM (0.37) | PKMPOLBGAACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |