Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822139 | 0.83 | RECQL (0.35) | ALDH1A1KDM4ERECQLHTT | |
| SCHEMBL9822135 | 0.82 | TP53 (0.37) | TP53LMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9822243 | 0.79 | TP53 (0.33) | TP53LMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9141819 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2KDM4ENPSR1MAPT | |
| SCHEMBL9822404 | 0.75 | KDM4E (0.37) | TP53ALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9143886 | 0.74 | ALDH1A1 (0.34) | TP53LMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9822408 | 0.72 | PDE10A (0.35) | TP53LMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9822117 | 0.72 | RECQL (0.33) | ALDH1A1RECQLHTT | |
| SCHEMBL9822174 | 0.71 | RECQL (0.53) | TP53ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL10407464 | 0.71 | MEN1 (0.38) | TP53LMNAALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |