Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822454 | 1.00 | MAOB (0.59) | MAOBPTGS2SNCAABCG2MAPT | |
| SCHEMBL9822724 | 0.84 | SNCA (0.42) | MAOBSNCAABCG2MAPTHSPD1 | |
| SCHEMBL9822534 | 0.84 | SNCA (0.42) | MAOBSNCAABCG2MAPTHSPD1 | |
| SCHEMBL9822466 | 0.83 | MAPT (0.56) | MAPTLMNA | |
| SCHEMBL9822438 | 0.81 | CYP26A1 (0.60) | MAOBPTGS2LMNA | |
| SCHEMBL9822432 | 0.81 | CYP26A1 (0.60) | MAOBPTGS2LMNA | |
| SCHEMBL10335899 | 0.78 | MAOB (0.39) | MAOBPTGS2SNCAABCG2MAPT | |
| SCHEMBL10336686 | 0.78 | MAOB (0.40) | MAOBSNCAABCG2MAPTMAOA | |
| SCHEMBL9822480 | 0.77 | PTGS2 (0.40) | MAOBPTGS2AKR1C3 | |
| SCHEMBL9822581 | 0.76 | RARA (0.47) | MAOBPTGS2LMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297995-B1 | POLYCYCLIC AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND ANIMAL MEDICINE AND IN COSMETICS | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |