Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822584 | 0.84 | PTGS2 (0.39) | PTGS2AKR1C3 | |
| SCHEMBL9822526 | 0.84 | RXRA (0.34) | RXRA | |
| SCHEMBL9822462 | 0.81 | RXRA (0.34) | AKR1C3RXRA | |
| SCHEMBL9822434 | 0.81 | RXRA (0.53) | RXRA | |
| SCHEMBL9822447 | 0.77 | MAOB (0.59) | PTGS2AKR1C3MAOB | |
| SCHEMBL9822454 | 0.77 | MAOB (0.59) | PTGS2AKR1C3MAOB | |
| SCHEMBL9822470 | 0.70 | RXRA (0.52) | RXRA | |
| SCHEMBL9822439 | 0.68 | RARA (0.47) | PTGS2AKR1C3MAOB | |
| SCHEMBL9822581 | 0.68 | RARA (0.47) | PTGS2AKR1C3MAOB | |
| SCHEMBL4407340 | 0.67 | RXRA (0.48) | RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297995-B1 | POLYCYCLIC AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND ANIMAL MEDICINE AND IN COSMETICS | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |