Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822840 | 0.81 | PARP1 (0.46) | PARP1KDM4EGLABRD4TDP1 | |
| SCHEMBL9822911 | 0.75 | PGR (0.34) | KDM4EBRD4TDP1ALDH1A1 | |
| SCHEMBL10370905 | 0.72 | ALDH1A1 (0.40) | KDM4ETDP1ALDH1A1 | |
| SCHEMBL9868369 | 0.69 | PARP1 (0.42) | PARP1BRD4TDP1 | |
| SCHEMBL10814991 | 0.67 | BRD4 (0.48) | PARP1BRD4TDP1 | |
| SCHEMBL10810657 | 0.67 | PARP1 (0.42) | PARP1 | |
| SCHEMBL10805151 | 0.66 | PARP1 (0.50) | PARP1BRD4TDP1 | |
| SCHEMBL9867744 | 0.66 | PARP1 (0.47) | PARP1BRD4TDP1 | |
| SCHEMBL14907125 | 0.65 | TDP1 (0.52) | PARP1KDM4ETDP1ALDH1A1GAA | |
| SCHEMBL9867437 | 0.64 | PARP1 (0.45) | PARP1KDM4EBRD4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231139-B1 | DIHYDROBENZOFURANE AND CHROMANE CARBOXAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS NEUROLEPTICS | Laboratoires DELAGRANGE (FR) | 1991-12-04 | — | — | EP | claimed |