Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 9/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | CBFB | Q13951 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980587 | 0.80 | GABRA2 (0.40) | GABRA2GABRB2KDM4EL3MBTL1GRIN2B | |
| SCHEMBL2831553 | 0.79 | MAPT (0.40) | GABRA2GABRB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL980293 | 0.74 | RORC (0.37) | GABRA2GABRB2KDM4EL3MBTL1GRIN2B | |
| SCHEMBL6864489 | 0.71 | GABRA2 (0.37) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL15568529 | 0.68 | RORC (0.59) | — | |
| SCHEMBL10678734 | 0.67 | GABRA2 (0.38) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL2829188 | 0.67 | MAPT (0.42) | GABRA2GABRB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6867884 | 0.66 | HPGD (0.36) | GABRA2GABRB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL3930034 | 0.65 | PTPN6 (0.44) | KDM4EL3MBTL1PTPN6PTPN11SMN1; SMN2 | |
| SCHEMBL2827266 | 0.65 | BIRC5 (0.50) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 2011-01-27 | — | — | US | disclosed |
| CN-101675056-A | Heterocyclic compounds and their use as pesticides | NOVARTIS AG | 2010-03-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | DDT, TYR, CAT | GABRA2 1490/4885GABRB2 1376/4885KDM4E 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.