Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830711 | 0.85 | HPGD (0.44) | RORCMAPTHPGDNPSR1HTT | |
| SCHEMBL980587 | 0.82 | GABRA2 (0.40) | RORCMAPTHPGDNPSR1HTT | |
| SCHEMBL982286 | 0.74 | GABRA2 (0.39) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL2829556 | 0.74 | RORC (0.37) | RORCMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL2828899 | 0.71 | HPGD (0.43) | RORCMAPTHPGDNPSR1HTT | |
| SCHEMBL2834112 | 0.70 | GABRA2 (0.43) | MAPTHPGDNPSR1HTTALDH1A1 | |
| SCHEMBL2831134 | 0.69 | HPGD (0.41) | MAPTHPGDNPSR1HTTALDH1A1 | |
| SCHEMBL2828429 | 0.68 | GABRA2 (0.45) | RORCMAPTHPGDNPSR1HTT | |
| SCHEMBL4415348 | 0.68 | GABRA2 (0.40) | RORCL3MBTL1GABRA2GABRB2CYP3A4 | |
| SCHEMBL2829188 | 0.65 | MAPT (0.42) | RORCMAPTHPGDNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | DDT, TYR, CAT | RORC 2101/4885MAPT 2897/4885HPGD 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.