Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822683 | 0.93 | DRD2 (0.51) | DRD2 | |
| SCHEMBL9868987 | 0.93 | DRD2 (0.51) | DRD2 | |
| Hydrochloric Acid SCHEMBL9868756 | 0.92 | DRD2 (0.51) | DRD2 | |
| SCHEMBL10810631 | 0.81 | CA2 (0.60) | DRD2 | |
| SCHEMBL9822699 | 0.78 | DRD2 (0.47) | DRD2 | |
| SCHEMBL9868584 | 0.78 | DRD2 (0.49) | DRD2 | |
| SCHEMBL9868144 | 0.77 | DRD2 (0.51) | DRD2 | |
| SCHEMBL9822863 | 0.77 | DRD2 (0.51) | DRD2 | |
| SCHEMBL9866760 | 0.77 | DRD2 (0.52) | DRD2 | |
| SCHEMBL9868166 | 0.77 | KEAP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231139-B1 | DIHYDROBENZOFURANE AND CHROMANE CARBOXAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS NEUROLEPTICS | Laboratoires DELAGRANGE (FR) | 1991-12-04 | — | — | EP | claimed |
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | claimed |
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |