SCHEMBL9823253

SCHEMBL9823253

C=C(O)Cc1cc(C#N)cs1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328878 0.76
SCHEMBL127800 0.76
SCHEMBL2325742 0.72
SCHEMBL1468083 0.72
Hydrochloric Acid SCHEMBL1467425 0.71 LOXL2 (0.39)
SCHEMBL5879612 0.70 GPR35 (0.34) EGLN1
SCHEMBL25363990 0.69 LOXL2 (0.44)
SCHEMBL21974405 0.69 MEN1 (0.36)
SCHEMBL13948555 0.69 LTB4R (0.43)
SCHEMBL17809501 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0314464-B1 THIOPHENE DERIVATIVES LILLY INDUSTRIES LIMITED (GB) 1991-09-04 EP disclosed
US-4886885-A Compound containing tetrazolyl groups and their use for treating allergies and cardiovascular disease LILLY INDUSTRIES LIMITED (GB) 1989-12-12 US disclosed
EP-0314464-A1 Thiophene derivatives LILLY INDUSTRIES LIMITED (GB) 1989-05-03 EP disclosed