Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580377 | 0.81 | CYP3A4 (0.39) | TSHRCYP3A4MAPK1LMNAGAA | |
| SCHEMBL9003125 | 0.77 | ACHE (0.42) | TSHRCYP3A4ACHEMAPK1GAA | |
| SCHEMBL9823273 | 0.74 | TSHR (0.38) | TSHRCYP3A4CCR5ACHEMAPK1 | |
| SCHEMBL9307823 | 0.71 | TSHR (0.49) | TSHRCYP3A4ACHEMAPK1LMNA | |
| SCHEMBL27690100 | 0.70 | TSHR (0.67) | TSHRCYP3A4LMNAGAAKMT2A | |
| SCHEMBL4235665 | 0.69 | CYP3A4 (0.50) | TSHRCYP3A4ACHEMAPK1LMNA | |
| SCHEMBL10737465 | 0.69 | TSHR (0.43) | TSHRCYP3A4LMNAGAASMN1; SMN2 | |
| SCHEMBL9002978 | 0.68 | EZH2 (0.40) | TSHRCYP3A4ACHEGAASMN1; SMN2 | |
| SCHEMBL11694221 | 0.66 | MAPK1 (0.43) | TSHRCYP3A4ACHEMAPK1LMNA | |
| SCHEMBL27839363 | 0.66 | TSHR (0.48) | TSHRCYP3A4LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410970-A4 | REACTIVE HINDERED AMINE LIGHT STABILIZERS | — | 1991-07-31 | — | — | EP | disclosed |
| EP-0410970-A1 | REACTIVE HINDERED AMINE LIGHT STABILIZERS. | ATOCHEM NORTH AMERICA (US) | 1991-02-06 | — | — | EP | disclosed |