Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580305 | 0.83 | GAA (0.37) | CYP3A4GAANAMPT | |
| SCHEMBL9823262 | 0.81 | TSHR (0.38) | CYP3A4TSHRLMNAGAAMAPK1 | |
| SCHEMBL9200819 | 0.72 | GAA (0.37) | TSHRLMNAGAASMN1; SMN2HPGD | |
| SCHEMBL9003125 | 0.70 | ACHE (0.42) | CYP3A4TSHRGAAMAPK1ALDH1A1 | |
| SCHEMBL27839363 | 0.67 | TSHR (0.48) | CYP3A4TSHRLMNAGAANAAA | |
| SCHEMBL9823273 | 0.67 | TSHR (0.38) | CYP3A4TSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL9002978 | 0.67 | EZH2 (0.40) | CYP3A4TSHRGAASMN1; SMN2 | |
| SCHEMBL9300565 | 0.66 | LMNA (0.37) | CYP3A4TSHRLMNAGAAMAPK1 | |
| SCHEMBL9307823 | 0.65 | TSHR (0.49) | CYP3A4TSHRLMNAGAAMAPK1 | |
| SCHEMBL27839365 | 0.65 | HDAC3 (0.40) | CYP3A4TSHRLMNAGAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5213897-A | Curable coating compositions containing an N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazide | ELF ATOCHEM NORTH AMERICA, INC. | 1993-05-25 | — | — | US | disclosed |