Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003674 | 0.87 | KDM4E (0.57) | PTGDR2ALOX5KDM4EALDH1A1RAB9A | |
| SCHEMBL3417072 | 0.84 | KDM4E (0.61) | ALOX5KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL5195843 | 0.84 | PTGDR2 (0.52) | PTGDR2ALOX5KDM4EALDH1A1RAB9A | |
| SCHEMBL10552788 | 0.83 | TARBP2 (0.57) | KDM4EALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL3995172 | 0.82 | RARA (0.60) | ALOX5KDM4EALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL6503223 | 0.81 | RARA (0.49) | PTGDR2ALOX5KDM4ERAB9ANPC1 | |
| SCHEMBL6496085 | 0.81 | KDM4E (0.63) | PTGDR2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL3419091 | 0.80 | RAB9A (0.74) | PTGDR2ALOX5KDM4EALDH1A1RAB9A | |
| SCHEMBL7898920 | 0.79 | RARB (0.47) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13898561 | 0.78 | PTGDR2 (0.56) | PTGDR2ALOX5KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |