Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.73 |
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15602692 | 0.87 | HTR2B (0.56) | HTR2BACHEKDM4EHPGDSCASP3 | |
| Pulicatins F SCHEMBL12469099 | 0.85 | HTR2B (1.00) | HTR2BACHECASP3RAB9ASMN1; SMN2 | |
| SCHEMBL9823114 | 0.83 | ACHE (0.60) | HTR2BACHEKDM4EHPGDSALDH1A1 | |
| SCHEMBL2693403 | 0.83 | ACHE (0.63) | HTR2BACHEKDM4EHPGDSALDH1A1 | |
| SCHEMBL3536997 | 0.81 | ACHE (0.66) | HTR2BACHEKDM4EHPGDSALDH1A1 | |
| SCHEMBL2691637 | 0.81 | ACHE (0.61) | HTR2BACHEKDM4EHPGDSRAB9A | |
| SCHEMBL2545992 | 0.81 | ACHE (0.61) | HTR2BACHEKDM4EHPGDSALDH1A1 | |
| SCHEMBL6183496 | 0.81 | ACHE (0.66) | HTR2BACHEKDM4EHPGDSALDH1A1 | |
| SCHEMBL6251863 | 0.81 | ACHE (0.61) | HTR2BACHEKDM4EHPGDSALDH1A1 | |
| SCHEMBL26320404 | 0.81 | ACHE (0.61) | HTR2BACHEKDM4EHPGDSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033151-B1 | HYDROXYPHENYL-THIAZOLE-THIAZOLINE AND -THIAZOLIDINE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THESE COMPOUNDS FOR USE IN INFLUENCING THE COLLAGEN METABOLISM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-02 | — | — | EP | claimed |
| US-20260026508-A1 | Seed Treatment Formulations and Methods of Use | PUNA BIO CORP (US) | 2026-01-29 | — | — | US | disclosed |
| WO-2023170024-A1 | CAMK2 MODULATORS AND THEIR USE IN MEDICINE | UNIVERSITY OF COPENHAGEN (DK) | 2023-09-14 | — | — | WO | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-9751847-B2 | Methods and compositions related to neuroactive thiazoline compounds | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-9751847-B2 | Methods and compositions related to neuroactive thiazoline compounds | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-3027754-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | enEvolv, Inc. (US) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015017866-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. (US) | 2015-02-05 | — | — | WO | disclosed |
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-01-16 | — | — | US | disclosed |
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-01-16 | — | — | US | disclosed |
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |
| EP-0033151-B1 | HYDROXYPHENYL-THIAZOLE-THIAZOLINE AND -THIAZOLIDINE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THESE COMPOUNDS FOR USE IN INFLUENCING THE COLLAGEN METABOLISM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | TACR2, TACR3, TACR1 | HTR2B 58/4885ACHE 167/4885KDM4E 4513/4885 |
| US-20260026508-A1 | Seed Treatment Formulations and Methods of Use | PGLS, GNE, GALE | HTR2B 4667/4885ACHE 386/4885KDM4E 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.