Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536997 | 0.83 | ACHE (0.66) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL6227066 | 0.83 | HPGD (0.60) | ACHEHTR2BHPGDSMAOAHDAC1 | |
| SCHEMBL9823334 | 0.81 | HTR2B (0.73) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL2693403 | 0.81 | ACHE (0.63) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL3537686 | 0.81 | ACHE (0.62) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL2545992 | 0.80 | ACHE (0.61) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL6251863 | 0.80 | ACHE (0.61) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL2691637 | 0.80 | ACHE (0.61) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL26320404 | 0.80 | ACHE (0.61) | ACHEALDH1A1KDM4EHTR2BHPGDS | |
| SCHEMBL5343313 | 0.80 | ALDH1A1 (0.62) | ACHEALDH1A1KDM4EHPGDSMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969902-A | Compound containing phenylthiazole acylhydrazone structure, and preparation and application thereof | 长江大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-116969929-A | 2- (sulfinyl-5- (2-phenylthiazol-4-yl) -1,3, 4-oxa (thia) diazole compounds, and preparation method and application thereof | 长江大学 | 2023-10-31 | — | — | CN | disclosed |
| EP-1161415-B1 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARM INC (US) | 2005-07-13 | — | — | EP | disclosed |
| US-6593327-B2 | N-cyanomethyl amides which are cysteine protease inhibitors; treating osteoporosis; mixtures with bisphosphonates | AXYS PHARMACEUTICALS, INC. | 2003-07-15 | — | — | US | disclosed |
| US-20030119788-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-06-26 | — | — | US | disclosed |
| US-6476026-B1 | Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-11-05 | — | — | US | disclosed |
| CN-1362947-A | N-cyanomethylamides as protease inhibitors | AXYS PHARM INC (US) | 2002-08-07 | — | — | CN | disclosed |
| US-20020086996-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | US | disclosed |
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086996-A1 | Novel compounds and compositions as protease inhibitors | CTRL, SERPINB1, CPN1 | ACHE 437/4885ALDH1A1 4049/4885KDM4E 2428/4885 |
| US-20030119788-A1 | Novel compounds and compositions as protease inhibitors | CTRL, SERPINB1, CPN1 | ACHE 437/4885ALDH1A1 4049/4885KDM4E 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.