Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.42 |
| ▸ | PIM1 | P11309 | 4/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823416 | 0.84 | IRAK4 (0.51) | KDM4EHSD17B10TLR7PDE4BIRAK4 | |
| SCHEMBL10553815 | 0.84 | PTGER1 (0.50) | TLR7 | |
| SCHEMBL9823609 | 0.83 | IRAK4 (0.50) | KDM4EHSD17B10TLR7PDE4BIRAK4 | |
| SCHEMBL9823630 | 0.83 | IRAK4 (0.50) | KDM4EHSD17B10TLR7PDE4BIRAK4 | |
| SCHEMBL9823191 | 0.82 | IRAK4 (0.42) | TLR7PDE5AIRAK4 | |
| SCHEMBL9823239 | 0.79 | TDP1 (0.44) | TLR7IRAK4 | |
| SCHEMBL9823503 | 0.79 | IRAK4 (0.48) | TLR7IRAK4 | |
| SCHEMBL9823240 | 0.79 | ACHE (0.51) | CNR2FAAHKDM4EPDE5APDE4A | |
| SCHEMBL9823137 | 0.78 | HTR2B (0.53) | KDM4ETLR7IRAK4 | |
| SCHEMBL9823486 | 0.77 | HTR2B (0.52) | KDM4ETLR7IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |