Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823429 | 0.71 | ALDH1A1 (0.58) | ALDH1A1CYP1A2OPRK1OPRM1OPRD1 | |
| SCHEMBL9823389 | 0.67 | MAPK1 (0.62) | ALDH1A1CYP1A2OPRK1OPRM1OPRD1 | |
| SCHEMBL9823499 | 0.66 | OPRK1 (0.40) | ALDH1A1CYP1A2OPRK1OPRM1OPRD1 | |
| SCHEMBL9823270 | 0.66 | OPRK1 (0.42) | ALDH1A1CYP1A2OPRK1OPRM1OPRD1 | |
| SCHEMBL8139218 | 0.65 | SLC6A2 (0.44) | ALDH1A1CYP1A2OPRK1OPRM1OPRD1 | |
| SCHEMBL20028764 | 0.64 | NOTUM (0.46) | ALDH1A1CYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL14060543 | 0.64 | ALDH1A1 (0.69) | ALDH1A1CYP1A2OPRK1SLC6A3SLC6A2 | |
| SCHEMBL1177971 | 0.63 | ALDH1A1 (0.68) | ALDH1A1CYP1A2OPRK1SLC6A3SLC6A2 | |
| SCHEMBL11257114 | 0.61 | ALDH1A1 (0.68) | ALDH1A1CYP1A2OPRK1SLC6A3SLC6A2 | |
| SCHEMBL6264784 | 0.61 | CYP3A4 (0.62) | ALDH1A1CYP1A2OPRK1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240050-B1 | A METHOD FOR CONTROLLING WEEDS | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-06-26 | — | — | EP | claimed |